منابع مشابه
Regenerative Strategies for Craniofacial Disorders
Craniofacial disorders present markedly complicated problems in reconstruction because of the complex interactions of the multiple, simultaneously affected tissues. Regenerative medicine holds promise for new strategies to improve treatment of these disorders. This review addresses current areas of unmet need in craniofacial reconstruction and emphasizes how craniofacial tissues differ from the...
متن کاملOral and Craniofacial Diseases and Disorders
Dental caries develops by the localized dissolution of the tooth hard tissues, caused by acids that are produced by bacteria in the biofilms (dental plaque) on the teeth and eventually lead to “cavities.” The biofilm consists of microorganisms, including the highly cariogenic mutans streptococci, and a matrix made up mainly of extracellular polysaccharides. The destructive acids are produced wh...
متن کاملCraniofacial Fibrous Dysplasia
Fibrous dysplasia (FD) is an osseous growth dis-order, producing immature bone and characte-rized by the replacement of normal bone with fibro-osseous connective tissue. It is a bone dys-plasia that has the potential to cause significant cosmetic and functional disturbances, particularly in the craniofacial skeleton. Cra-niofacial fibrous dysplasia is one of the three types of polyostotic fibro...
متن کاملA review of craniofacial disorders caused by spliceosomal defects.
The spliceosome is a large ribonucleoprotein complex that removes introns from pre-mRNA transcripts. Mutations in EFTUD2, encoding a component of the major spliceosome, have recently been identified as the cause of mandibulofacial dysostosis, Guion-Almeida type (MFDGA), characterized by mandibulofacial dysostosis, microcephaly, external ear malformations and intellectual disability. Mutations i...
متن کاملSingle gene disorders with craniofacial and oral manifestations.
Gene and environmental factors are instrumental in genesis of complex and wide range of disorders and syndromes. The newer gene sequencing and other advanced technologies have made our previous knowledge of genetic etiopathogenesis of various disorders more transparent. Single gene disorders refer to the disorders caused due to mutations in a single gene and a fair number of these manifest as c...
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ژورنال
عنوان ژورنال: Australian Dental Journal
سال: 2018
ISSN: 0045-0421
DOI: 10.1111/adj.12591